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清醒

清醒是指在不感到困倦的情况下保持意识的能力增强，同时伴随着睡眠需求的减少哦。[1] 这与刺激（Stimulation）有所不同呢，因为它不会直接将人的能量水平提升到正常基线以上，而是产生一种清醒、休息充分和警觉的感觉嘛。[2][3] 如果在使用这种物质之前感到困倦，睡眠的冲动会消退，睁开眼睛会变得更容易，疲惫带来的认知迷雾也会减少哦。[4] 然而，在极端情况下，积累了足够的睡眠不足还是会压倒或抵消这种效果的呢。[2]

清醒通常是在中等（Common）剂量的各种化合物影响下产生的，比如兴奋剂、益智药和迷幻剂哦。不过值得注意的一点是，有少数化合物能选择性地诱导这种效果，而不会伴随许多其他副作用，这些被称为觉醒剂（eugeroics）或促清醒剂呢。其中包括莫达菲尼[2][3][5][6]和阿莫达菲尼（armodafinil）[2]。

目录

体验报告

在我们的体验索引中，描述此效应的轶事报告包括：

  • Experience: 15mg 2C-B (oral) - A pleasant low-dose evening with Nexus_-_A_pleasant_low-dose_evening_with_Nexus.md)
  • Experience:100-350mg - Phenylpiracetam in daily life
  • Experience:1000 Morning Glory seeds - Rediscovering the Self
  • Experience:120mg - Garden of The Gods
  • Experience:1g Methiopropamine - Chasing the Chalky Dragon
  • Experience:25mg - A labyrinth of organs and a storybook walk
  • Experience:300mg DPH + 600mg DXM - An Interesting Combo
  • Experience:300µg LSD - Togetherness and the Silent Dusk
  • Experience:30mg - Psychostimulant egodeath
  • Experience:30mg Isopropylphenidate - IPPH As A Study Aid
  • Experience:37mg Isopropylphenidate - Getting Shit Done With Isopropylphenidate
  • Experience:75mg 3-FMA - Perfect Blend of Euphoria and Functionality
  • Experience:800 seeds LSA - My First Trip Ever
  • Experience:BK-2C-B - Various experiences
  • Experience:LSA (20 HWBR seeds) – A pleasant adventure with a harsh body load_%E2%80%93_A_pleasant_adventure_with_a_harsh_body_load.md)
  • Experience:LSD (230 ug) - An amazing adventure by vikilikepsych_-_An_amazing_adventure_by_vikilikepsych.md)
  • Experience:Marijuana Withdrawal
  • Experience:Mushrooms and Snuff Films -- Trip Report (3.5 grams).md)
  • Experience:Zopiclone hppd?

另见

外部链接

参考文献

  1. ↑ Porkka-Heiskanen, T. (1997). "Adenosine: A Mediator of the Sleep-Inducing Effects of Prolonged Wakefulness". Science. 276 (5316): 1265–1268. doi:10.1126/science.276.5316.1265. ISSN 0036-8075. 
  2. ↑ 2.0 2.1 2.2 2.3 Repantis, Dimitris; Schlattmann, Peter; Laisney, Oona; Heuser, Isabella (2010). "Modafinil and methylphenidate for neuroenhancement in healthy individuals: A systematic review". Pharmacological Research. 62 (3): 187–206. doi:10.1016/j.phrs.2010.04.002. ISSN 1043-6618. 
  3. ↑ 3.0 3.1 Engber, T.M; Dennis, S.A; Jones, B.E; Miller, M.S; Contreras, P.C (1998). "Brain regional substrates for the actions of the novel wake-promoting agent modafinil in the rat: comparison with amphetamine". Neuroscience. 87 (4): 905–911. doi:10.1016/S0306-4522(98)00015-3. ISSN 0306-4522. 
  4. ↑ Caldwell, John A.; Caldwell, J. Lyn; Smyth, Nicholas K.; Hall, Kecia K. (2000). "A double-blind, placebo-controlled investigation of the efficacy of modafinil for sustaining the alertness and performance of aviators: a helicopter simulator study". Psychopharmacology. 150 (3): 272–282. doi:10.1007/s002130000450. ISSN 0033-3158. 
  5. ↑ Myrick, Hugh; Malcolm, Robert; Taylor, Brent; LaROWE, STEVEN (2004). "Modafinil: Preclinical, Clinical, and Post-Marketing Surveillance—A Review of Abuse Liability Issues". Annals of Clinical Psychiatry. 16 (2): 101–109. doi:10.1080/10401230490453743. ISSN 1040-1237. 
  6. ↑ Scammell, Thomas E.; Estabrooke, Ivy V.; McCarthy, Marie T.; Chemelli, Richard M.; Yanagisawa, Masashi; Miller, Matthew S.; Saper, Clifford B. (2000). "Hypothalamic Arousal Regions Are Activated during Modafinil-Induced Wakefulness". The Journal of Neuroscience. 20 (22): 8620–8628. doi:10.1523/JNEUROSCI.20-22-08620.2000. ISSN 0270-6474.