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去抑制

去抑制在医学上被认为是一种倾向于立即满足的心理导向，导致在当前的思想、感觉和外部刺激驱动下产生的冲动行为，而不考虑过去的学习经验或未来的后果哦。[1][2][3] 这通常通过鲁莽、糟糕的风险评估和无视社会习俗表现出来呢。

在较低的强度水平下，去抑制可以让一个人克服情感上的忧虑和受压抑的社交技能，这种方式对普通人来说是适度且可控的。这通常对那些遭受社交焦虑或普遍缺乏自信的人很有帮助嘛。

然而，在较高的强度水平下，去抑制的个体可能完全无法保持任何形式的自我克制，这是以牺牲礼貌、敏感度、社交得体性或地方法律法规为代价的。这种约束的缺失可能是消极的、中性的或积极的，这取决于个人和他们当前的环境呢。去抑制行为的负面后果范围很广，从相对温和的后果（比如让自己尴尬）到破坏性和破坏性的后果（比如酒后驾车或犯罪行为）都有可能哦。

去抑制通常伴随着其他同时发生的效应，比如健忘（Amnesia）和焦虑抑制（Anxiety suppression），这种方式会进一步降低人们对社会规范的遵守和重视呢。它最常在中等（Common）剂量的GABA能抑制剂影响下产生，比如酒精、[4] 苯二氮卓类物质、[5] 菲尼布特和GHB。不过嘛，它也可能出现在某些兴奋剂、[6] 共情剂[7]和解离剂[8]的影响下哦。

目录

体验报告

在我们的体验索引中，描述此效应的轶事报告包括：

  • Experience: 36mg 4-AcO-DiPT - Truly, one for the psychedelic animals among us
  • Experience:100 mg- Actually Lifechanging
  • Experience:20mg Etizolam - Smoking Etizolam
  • Experience:260 mg Ketamine (insufflated) - Lost in Paisley_-_Lost_in_Paisley.md)
  • Experience:3-MeO-PCP - Extreme psychosis
  • Experience:3-MeO-PCP, LSD, Clonazolam, and Amphetamine - Excessive Amounts and Excessive Confusion
  • Experience:3mg Etizolam - A Comedown Drug
  • Experience:400mg and 300mg of fluorophenibut
  • Experience:60mg Zolpidem - A Delirious Adventure
  • Experience:Alprazolam (24 mg) - Into the Void_-_Into_the_Void.md)
  • Experience:Clonazolam + 2-methyl-AP-237 (unknown dosage) - Cardiac arrest_-_Cardiac_arrest.md)
  • Experience:DXM & DPH in combination
  • Experience:Psilocybin Mushroom (0.16 g, Oral) - Dosage Independent Intensity_-_Dosage_Independent_Intensity.md)
  • Experience:Zopiclone hppd?

另见

外部链接

参考文献

  1. ↑ "Glossary of Technical Terms". Diagnostic and statistical manual of mental disorders (5th ed.): 820. 2013. doi:10.1176/appi.books.9780890425596.GlossaryofTechnicalTerms. 
  2. ↑ Zamboni, G.; Huey, E. D.; Krueger, F.; Nichelli, P. F.; Grafman, J. (2008). "Apathy and disinhibition in frontotemporal dementia: Insights into their neural correlates". Neurology. 71 (10): 736–742. doi:10.1212/01.wnl.0000324920.96835.95. ISSN 0028-3878. 
  3. ↑ Källmén, Håkan; Gustafson, Roland (1998). "Alcohol and Disinhibition". European Addiction Research. 4 (4): 150–162. doi:10.1159/000018948. ISSN 1022-6877. 
  4. ↑ Bettinger, Jill C.; Topper, Stephen M.; Aguilar, Sara C.; Topper, Viktoria Y.; Elbel, Erin; Pierce-Shimomura, Jonathan T. (2014). "Alcohol Disinhibition of Behaviors in C. elegans". PLoS ONE. 9 (3): e92965. doi:10.1371/journal.pone.0092965. ISSN 1932-6203. 
  5. ↑ Paton, Carol (2018). "Benzodiazepines and disinhibition: a review". Psychiatric Bulletin. 26 (12): 460–462. doi:10.1192/pb.26.12.460. ISSN 0955-6036. 
  6. ↑ Fillmore, M (2003). "Effects of d-amphetamine on behavioral control in stimulant abusers: the role of prepotent response tendencies". Drug and Alcohol Dependence. 71 (2): 143–152. doi:10.1016/S0376-8716(03)00089-9. ISSN 0376-8716. 
  7. ↑ Ando, Romeo D.; Benko, Anita; Ferrington, Linda; Kirilly, Eszter; Kelly, Paul A.T.; Bagdy, Gyorgy (2006). "Partial lesion of the serotonergic system by a single dose of MDMA results in behavioural disinhibition and enhances acute MDMA-induced social behaviour on the social interaction test". Neuropharmacology. 50 (7): 884–896. doi:10.1016/j.neuropharm.2005.12.010. ISSN 0028-3908. 
  8. ↑ Lissek, Silke; Güntürkün, Onur (2003). "Dissociation of Extinction and Behavioral Disinhibition: The Role of NMDA Receptors in the Pigeon Associative Forebrain during Extinction". The Journal of Neuroscience. 23 (22): 8119–8124. doi:10.1523/JNEUROSCI.23-22-08119.2003. ISSN 0270-6474.