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强迫性补量

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强迫性补量被定义为一种强烈且难以抵抗的冲动，想要不断地追加服用精神活性物质，试图增加或维持其引发的主观效应呢。[1][2][3][4]

当使用者手头有大量这种物质时，这种效应会明显更容易出现哦。可以通过预先称量好剂量、不要把剩下的东西放在眼皮子底下、发挥自我控制力，或者把东西交给信任的人保管直到他们认为安全归还为止，来部分避免这种情况嘛。

强迫性补量通常伴随着其他并发效应，比如认知欣快、躯体欣快或焦虑抑制，以及其他会抑制判断清晰度的效应，例如去抑制、动机增强和自我膨胀。这种现象最常在中等剂量的各类化合物影响下被诱发，比如阿片类药物、兴奋剂、[2][4][5] GABA类物质[2]以及共情剂呢。[3] 不过，在解离剂和大麻类物质的影响下，也可能出现程度较轻的这种情况哦。[3]

体验报告

在我们的体验索引中，描述此效应的轶事报告包括：

  • Experience: 36mg 4-AcO-DiPT - Truly, one for the psychedelic animals among us
  • Experience:1.2 g gabapentin, alcohol, and half of 150 mg Effexor XR - Pretty lovely for socializing and giggles
  • Experience:100/100/100mg, first time with it
  • Experience:110mg Diphenidine (vaporized) + 354mg DXM - instant ego death_%2B_354mg_DXM_-_instant_ego_death)
  • Experience:1g Methiopropamine - Chasing the Chalky Dragon
  • Experience:20mg Etizolam - Smoking Etizolam
  • Experience:20mg Heroin - The Last Time I Shot Up
  • Experience:25mg 3-MeO-PCP - Enhanced film experience
  • Experience:25mg Deschloroketamine - My first time orally dosing DCK
  • Experience:260 mg Ketamine (insufflated) - Lost in Paisley_-_Lost_in_Paisley)
  • Experience:2mg Etizolam & N2O - "Hippy Crack" Indeed
  • Experience:2mg Etizolam - Here be dragons
  • Experience:3-MeO-PCP - Extreme psychosis
  • Experience:3-MeO-PCP, LSD, Clonazolam, and Amphetamine - Excessive Amounts and Excessive Confusion
  • Experience:30mg Isopropylphenidate - IPPH As A Study Aid
  • Experience:37mg Isopropylphenidate - Getting Shit Done With Isopropylphenidate
  • Experience:3mg Etizolam - A Comedown Drug
  • Experience:60mg Zolpidem - A Delirious Adventure
  • Experience:A night with Ethylphenidate
  • Experience:Alprazolam (24 mg) - Into the Void_-_Into_the_Void)
  • Experience:Datura and nicotine smoked - 4 and ~15 hits; was actually quite pleasant
  • Experience:FMA (37.5 mg, oral) - Never been this productive in my life_-_Never_been_this_productive_in_my_life)
  • Experience:Nitrous oxide (approx. 50 puffs) - ~50 puffs nitrous oxide_-_~50_puffs_nitrous_oxide)

另见

外部链接

References

  1. ↑ Everitt, Barry J; Robbins, Trevor W (2005). "Neural systems of reinforcement for drug addiction: from actions to habits to compulsion". Nature Neuroscience. 8 (11): 1481–1489. doi:10.1038/nn1579. ISSN 1097-6256. 
  2. ↑ 2.0 2.1 2.2 Volkow, N. D. (2000). "Addiction, a Disease of Compulsion and Drive: Involvement of the Orbitofrontal Cortex". Cerebral Cortex. 10 (3): 318–325. doi:10.1093/cercor/10.3.318. ISSN 1460-2199. 
  3. ↑ 3.0 3.1 3.2 Hyman, Steven E.; Malenka, Robert C. (2001). "Addiction and the brain: The neurobiology of compulsion and its persistence". Nature Reviews Neuroscience. 2 (10): 695–703. doi:10.1038/35094560. ISSN 1471-003X. 
  4. ↑ 4.0 4.1 Soussan, Christophe; Kjellgren, Anette (2015). ""Chasing the High" – Experiences of Ethylphenidate as Described on International Internet Forums". Substance Abuse: Research and Treatment. 9: SART.S22495. doi:10.4137/SART.S22495. ISSN 1178-2218. 
  5. ↑ Olives, Travis; Orozco, Benjamin; Stellpflug, Samuel (2012). "Bath Salts: The Ivory Wave of Trouble". Western Journal of Emergency Medicine. 13 (1): 58–62. doi:10.5811/westjem.2011.6.6782. ISSN 1936-900X. 
  6. ↑ Watterson LR, Kufahl PR, Nemirovsky NE, Sewalia K, Grabenauer M, Thomas BF, et al. (March 2014). "Potent rewarding and reinforcing effects of the synthetic cathinone 3,4-methylenedioxypyrovalerone (MDPV)". Addiction Biology. 19 (2): 165–74. doi:10.1111/j.1369-1600.2012.00474.x. PMC 3473160 Freely accessible. PMID 22784198. 
  7. ↑ Coppola M, Mondola R (January 2012). "3,4-methylenedioxypyrovalerone (MDPV): chemistry, pharmacology and toxicology of a new designer drug of abuse marketed online". Toxicology Letters. 208 (1): 12–5. doi:10.1016/j.toxlet.2011.10.002. PMID 22008731.